基本素養 Basic Literacy

核心能力 Competence

閱讀、理解與運用專業知識
培養學生具備一般及專業領域的研究素養,並富有國際視野之科學涵養
Good reading comprehension of scientific materials and excellent capabilities in applying professional knowledge
To train students to have good backgrounds in general and specialized fields and have global views of science
彙整新知與良好的溝通能力
培養學生具備彙整分子醫學新知與溝通表達研究成果的能力
Abilities of updating and organizing innovative knowledge and demonstrating good communicational skills
To train students to learn efficiently and to apply their knowledge effectively
生物醫學研究技術的應用與能力
培養學生具備生物醫學研究技術的應用與能力
The abilities and applications in biomedical research and technology
To train students in acquiring both the knowledge and practical applications in biomedical research & technology
解決研究問題的能力
培養學生具備獨立思考與從事分子醫學相關研究領域的能力
Problem-solving skills
To train students to become independent thinkers capable of conducting independent and innovative research in molecular medicine

課程概述 Course Description

在世界已開發國家中,因經濟高度發展及醫藥發達,社會高齡化趨勢與日俱增。因此,老人醫學是現在世界各國重視與加強發展的學門。重要的是,研究老化與老化相關的生命科學領域也正蓬勃發展。這門課程的目標,是期望將老化研究領域中的重要文獻背景做回顧,並探討最近的突破與發現。並希望藉由介紹老化研究領域的研究模式,讓學生能從單一細胞老化、到生物體的衰老的已知機制與模式能有廣泛的認知
This course is designed to cover the topics on aging and aging-related research disciplines, such as regulation of cellular senescence, model systems for aging research, aging genetics, signal transduction in aging process, anti-aging research, mitochondrial biology, DNA repair and chromosome stability in aging, and cancer in aging. After completing this course, students can gain novel concepts of aging and a broad view of aging-related research.

課程學習目標 Course Objectives

  • 讓學生能從單一細胞老化、到生物體的衰老理論有基本概念
  • 老化相關疾病如癌症、神經退化疾病的產生的已知機制有深入概念
  • 建立老化研究的細胞及動物模式的知識及運用老化研究模式的能力
  • 課程進度 Progress Description

    進度說明 Progress Description
    1Introduction to aging
    2The molecular genetics of aging
    3Aging in model organisms I
    4Aging in model organisms II
    5From cell dividing to cell senescence
    6Cell senescence, oncogene, and cancer
    7Mitochondria, Oxidative stress, and aging I
    8Mitochondria, Oxidative stress, and aging II
    9The molecular pathogenesis of Alzheimer’s disease in aging
    10Molecular basis of neurodegeneration
    11Drosophila as a model for human neurodegenerative disease
    12Calorie restriction and aging
    13Reproductive aging
    14Discussions on aging research (PBL)
    15The keys to longevity
    16Final report
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    課程是否與永續發展目標相關調查
    Survey of the conntent relevant to SDGs

    本課程與SDGs相關項目如下:
    This course is relevant to these items of SDGs as following:
    • 健康與福祉 (Good health and Well Being)

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No

    教師上傳大綱內容
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    111學年度 老化研究特論 010323.pdf