基本素養 Basic Literacy

核心能力 Competence

閱讀、理解與運用專業知識
培養學生具備一般及專業領域的研究素養,並富有國際視野之科學涵養
Good reading comprehension of scientific materials and excellent capabilities in applying professional knowledge
To train students to have good backgrounds in general and specialized fields and have global views of science
彙整新知與良好的溝通能力
培養學生具備彙整分子醫學新知與溝通表達研究成果的能力
Abilities of updating and organizing innovative knowledge and demonstrating good communicational skills
To train students to learn efficiently and to apply their knowledge effectively
生物醫學研究技術的應用與能力
培養學生具備生物醫學研究技術的應用與能力
The abilities and applications in biomedical research and technology
To train students in acquiring both the knowledge and practical applications in biomedical research & technology
解決研究問題的能力
培養學生具備獨立思考與從事分子醫學相關研究領域的能力
Problem-solving skills
To train students to become independent thinkers capable of conducting independent and innovative research in molecular medicine

課程概述 Course Description

旨在傳授有關細胞程序性死亡的分子機轉,特別是在細胞凋亡的方面。此課程的內容包含細胞程序性死亡及細胞凋亡的基本概念以及調控這些細胞死亡的分子機轉。指引學生對細胞程序性死亡能有更深入的瞭解,並探討在細胞程序性死亡研究領域的最新發現。
This course covers the topics of molecular mechanisms that regulate the programmed cell death (PCD), especially on apoptosis. Topics include an overview of PCD; introduction to apoptosis; molecular mechanisms regulating apoptosis and other non-apoptotic PCD such as necroptosis, pyroptosis and ferroptosis. The primary goal of this course is to let students gain mechanistic insights regarding apoptosis and non-apoptotic PCD and learn recent findings in the PCD field.

課程學習目標 Course Objectives

  • To gain insights and learn recent findings in the programmed cell death field
  • To train students to learn efficiently and to apply their knowledge effectively
  • To train students to have good backgrounds in general and in specialized fields
  • 課程進度 Progress Description

    進度說明 Progress Description
    1Introduction to the programmed cell death and apoptosis
    2The programmed cell death in C. elegans
    3The programmed cell death in development of Drosophila
    4The programmed cell death in murine development
    5The prosurvival Bcl-2 protein family
    6The pro-apoptotic Bcl-2 protein family
    7Mitochondria and apoptosis
    8Caspases
    9The extrinsic pathway of apoptosis
    10Apoptosis in the nervous system
    11Application of apoptosis in therapeutics
    12Non-apoptosis PCD I : Entosis, necroptosis, and aut
    13Non-apoptosis PCD II : Ferroptosis
    14Pathogens and PCD
    15Autophagy and apoptosis
    16Discussions on recent findings of PCD
    17Discussion
    18Discussion
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    課程是否與永續發展目標相關調查
    Survey of the conntent relevant to SDGs

    本課程與SDGs相關項目如下:
    This course is relevant to these items of SDGs as following:
    • 健康與福祉 (Good health and Well Being)

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No

    教師上傳大綱內容
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    111-1 細胞程序性死亡的分子機轉 課程 syllabus new.pdf