基本素養 Basic Literacy

核心能力 Competence

培養生物化學與分子生物學的專業知識
Biochemistry and molecular biology professional knowledge.
學習其他生物醫學與生物技術相關領域知識
Learn knowledge in other biology medicine and biology techniques fields.
培養閱讀與整理新知及表達研究成果的能力
Reading and collection new knowledge and presentation research results.
培養生物醫學各領域的知識技能與實驗設計能力與技能
Biology medicine knowledge in every field and experiment design and techniques.
加強獨立從事研究能力
Enhance independent research ability.

課程概述 Course Description

本課程將探討近年在表觀基因體調控機制的新知。包括DNA甲基化,組蛋白修飾,與細胞核的改變。
We will go through recent advances in understanding the regulation of the epigenome. This includes DNA methylation, histone modifications, and changes in nucleus.

課程學習目標 Course Objectives

  • 增進對Epigenetics領域之醫學生化與生物醫學研究之基礎與新知。
  • 提升全基因組分析方法學與科技於研究專題之應用。
  • 促進英文期刊論文之報告分析與討論。
  • 課程進度 Progress Description

    進度說明 Progress Description
    1Brief history, overview, and concepts of epigenetics
    2Chromatin modifications and transcriptional regulation
    3Histone variants
    4Epigenetic regulation of chromosome inheritance
    5DNA methylation, genomic imprinting, and dosage compensation in mammals
    6Epigenetics and human disease (I)
    7Epigenetics and human disease (II)
    8Epigenetics and human disease (III)
    9Germline, pluripotent stem cells, and epigenetic control of lymphopoiesis
    10Nuclear transportation and the reprogramming of the genome
    11Epigenetics in non-Mammals, and the Epigenetics 2.0 - the next generation
    12Epigenetics 2.0 -- the next generation (I)
    13Epigenetics 2.0 -- the next generation (II)
    14Epigenetics 2.0 -- the next generation (III)
    15Epigenetics 2.0 -- the next generation (IV)
    16Histone and DNA Modifications as Regulators of Neuronal Development and Function
    17Discussion and a view into future
    18Final report
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    課程是否與永續發展目標相關調查
    Survey of the conntent relevant to SDGs

    本課程與SDGs相關項目如下:
    This course is relevant to these items of SDGs as following:
    • 健康與福祉 (Good health and Well Being)
    • 就業與經濟成長 (Decent work and Economic growth)

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No