基本素養 Basic Literacy

核心能力 Competence

穩固基礎生物科技知識能力
Solid knowledge in fundamentals of biotechnology
具備生技產業前瞻視野
Bio-industry foresight
建構國際化能力
Capability of internationalization
培養獨立邏輯思維能力
Independent logical thinking
展現專業生技產業技術能力
Specialized bio-industry technique
養成科學邏輯表達能力
Capability of presenting scientific logic
培育學術責任倫理能力
Academic responsibility and ethics
培養跨領域整合與應用能力
Capability of interdisciplinary integration and application
具備自我發展與終身學習能力
Capability of self-development and lifelong education
發展領導經營及管理能力
Leadership in business and management
追求創新思考及解決問題能力
Capability of innovative thinking and problem solving
具備實踐與合作精神能力
Capability of execution and collaboration

課程概述 Course Description

所教授之課程內容將著重於介紹蛋白質及重要的分子遺傳物質核酸等生物巨分子的序列、特性、結構、以及其結構與功能之間的關係之基本知識為導論。亦針對最近幾年來在國際生物醫療領域備受重視之研究生物巨分子的新穎方法的發展及應用做概述。
The course covers the basics of biophysics for biomacromolecules, including protein and genetic materials. It begins with introducing the elements, characteristics, and structure of biomacromolecules, as well as the structure-function relationships. The course also introduces the latest and important developments of the methods, in the biomedical field, to study biomacromolecules, as well as their potential applications.

課程學習目標 Course Objectives

  • 了解生物巨分子的組成以及其各級結構的基本特質及重要特性,及結構與功能間的重要性。
  • 培養學生對於生命科學基礎知識的廣度,以及對於更深入的結構生物學課題研究的基礎。
  • 了解研究生物巨分子的新穎方法,提供畢業後銜接職場上,如生物製藥應用的能力。
  • 課程進度 Progress Description

    進度說明 Progress Description
    1Introduction of the course
    2From Sequence to Structure (Overview: Protein function and architecture)
    3From Sequence to Structure (including Amino acids, Genes and proteins, The peptide bonds, Importance and determinants of secondary structure)
    4From Sequence to Structure (including Properties of alpha helix, Properties of beta sheet, Tertiary structure, General principle of quaternary structure)
    5From Sequence to Structure (Intermolecular interfaces of quaternary structure, Nucleotide structures)
    6From Structure to Function (Overview: The structural basis of protein function)
    7From Structure to Function (including DNA recognition, Specific transcription factors)
    8From Structure to Function (including Enzyme catalysis, Membrane proteins)
    9Mid-term Exam (Oral presentation)
    10From Structure to Function (including Proteins in signal transductions, Recognition of foreign molecules by the immune system)
    11Determination of macromolecular structures (Brief Introduction of Experimental tools)
    12Determination of macromolecular structures(including CD spectrometry, NMR, X-ray crystallography)
    13 Determination of macromolecular structures(Introduction of Experimental methods, including SAD, MAD)
    14Determination of macromolecular structures(Introduction of useful websites for biomacromolecules analysis)
    15 Determination of macromolecular structures(Introduction of useful websites for the structural prediction of biomacromolecules)
    16Novel Methods in Biomedical drugs design
    17Final Exam (Oral presentation of the research articles)
    18Final Exam (Oral presentation of the research articles)
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No