基本素養 Basic Literacy
■ 人文素養
學生應具有尊重、關懷、及服務有關食品安全衛生對健康影響議題的素養。
Humanities literacy
Students should show respect, compassion, care, and willingness of providing service to Food Safety / Hygiene related issues.
□ 公民素養
學生應有以食品安全衛生及風險評估為主體的理念，具有主動、積極參與社會之精神，並運用相關知識解決問題的能力。
Citizenship literacy
Students should have the concept of Food Safety / Hygiene and risk assessment , take an active and positive role in social activities; be able to apply knowledge to solve problems.
□ 社會關懷
學生應對食品安全衛生相關議題的社會互動關聯展現高度的關心和參與。
Social care
Students should show high interest and actively participate in social interactions related to food safety and health issues
■ 國際視野
學生應具備地球村及污染無國界之國際視野，並將其扎根本土食品安全衛生議題。
International perspective
Student should have international perspectives of “global village” and “pollution without borders” and put them into context of local Food Safety / Hygiene issues.
核心能力 Competence
■ 食品安全衛生與健康風險評估能力
身為專業人員，解決食品安全衛生對健康影響議題及照顧民眾為其基本能力。
Food Safety / Hygiene and risk assessment capabilities
Students can serve as food safety, health and risk management professionals, with the ability to solve related issues and take care of the general public.
■ 安全食品產業鏈專業能力
認知與評估可能危害、理解相關機轉並運用專業能力控制危害因子、運用科學方法分析資料並撰寫報告、規劃食品安全衛生議題之解決及風險評估方案。
safety food industry chain capabilities
Students can recognize and evaluate the hazards, and control, use scientific methods to analyze data and report, for Food Safety/Hygiene and Risk Management.
□ 解決的能力
具備食品安全衛生議題之判斷能力，熟悉以安全衛生及風險評估相關專業知識解決所面對的議題。
Problem solving Skills
Students can accurately recognize Food Safety/Hygiene and be familiarized with solving problems using knowledge in Food Safety / Hygiene and risk assessment.
□ 良好的溝通能力
應具備與民眾溝通之能力，並能將專業的語言轉換成民眾理解的語言之能力。
Effective communication skills
Students can have the ability to communicate with the general public, and translate professional communications into plain language.
□ 終身學習的態度
具備主動探索食品安全衛生議題、具創新與領導能力、能有積極在職進修及終身學習之態度。
Life-long learning attitude
Possess the attitude and ability to actively explore Food Safety / Hygiene issues, innovate and lead in their job, and learn for the life-time.
課程概述 Course Description
本課程將介紹毒物造成生物體毒性之分子機轉，並介紹新穎之毒理基因體學包含高通量之轉譯體學、蛋白體學及代謝體學等研究方法，結合毒理分子機轉的介紹及新穎基因體學的研究方法，以評估或預測食品中潛在毒性物質之分子機轉。This course involves studying the molecular mechanisms of the toxic effects of xenobiotics on living organisms. Also combines the knowledge of toxicology with genomics and other high-throughput molecular profiling technologies including transcriptomics, proteomics and metabolomics. The aim of the course is to combine novel molecular mechanisms and toxicogenomic methodologies to study or predict the possible toxic mechanisms of xenobiotics existed in food.
課程學習目標 Course Objectives
課程進度 Progress Description
| 進度說明 Progress Description | |
|---|---|
| 1 | Introduction |
| 2 | Cell membrane receptors-Receptor tyrosine kinase |
| 3 | Cell membrane receptors - xenosensors |
| 4 | Post translational modification of proteins (I) |
| 5 | Post translational modification of proteins (II) |
| 6 | Paper Discussion |
| 7 | Transcriptional factors |
| 8 | Inflammation signals: Inflammasome and NFκB |
| 9 | Mid-term Exam |
| 10 | Cell death modalities I-apoptosis and necroptosis |
| 11 | Cell death modalities II-pyroptosis and ferroptosis |
| 12 | Paper Discussion |
| 13 | Cell death modalities III-autophagy and mitophagy |
| 14 | Prosurvival Signalings |
| 15 | Cell cycle regulation |
| 16 | Fibrosis Signalings |
| 17 | Paper Discussion |
| 18 | Final Exam |
以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.
課程是否與永續發展目標相關調查
Survey of the conntent relevant to SDGs
本課程與SDGs相關項目如下：
This course is relevant to these items of SDGs as following:
- 健康與福祉 (Good health and Well Being)
有關課程其他調查 Other Surveys of Courses
1.本課程是否規劃業界教師參與教學或演講? 否Is there any industry specialist invited in this course? How many times? No
2.本課程是否規劃含校外實習(並非參訪)? 否
Are there any internships involved in the course? How many hours? No
3.本課程是否可歸認為學術倫理課程? 否
Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
4.本課程是否屬進入社區實踐課程? 否
Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No