基本素養 Basic Literacy

核心能力 Competence

閱讀、理解與運用專業知識
培養學生具備一般及專業領域的研究素養,並富有國際視野之科學涵養
Good reading comprehension of scientific materials and excellent capabilities in applying professional knowledge
To train students to have good backgrounds in general and specialized fields and have global views of science
彙整新知與良好的溝通能力
培養學生具備彙整分子醫學新知與溝通表達研究成果的能力
Abilities of updating and organizing innovative knowledge and demonstrating good communicational skills
To train students to learn efficiently and to apply their knowledge effectively
生物醫學研究技術的應用與能力
培養學生具備生物醫學研究技術的應用與能力
The abilities and applications in biomedical research and technology
To train students in acquiring both the knowledge and practical applications in biomedical research & technology
解決研究問題的能力
培養學生具備獨立思考與從事分子醫學相關研究領域的能力
Problem-solving skills
To train students to become independent thinkers capable of conducting independent and innovative research in molecular medicine

課程概述 Course Description

本課程目標旨在探討腦神經內分泌系統與免疫系統之間的交互作用。課程內容涵蓋腦細胞之基本組成與傳遞機制;進而延伸至神經內分泌和免疫系統以及神經細胞與膠質細胞之間的相互調控。此課程不同於由傳統藥理學或生理學的角度來探討大腦神經的功能,而是由跨學科的角度來探究腦內不同細胞之間與大腦外的免疫系統如何維持正常生理功能和失衡時如何導致疾病發生。事實上,許多人類神經疾病的發生,便是腦內外免疫系統失能所造成,例如:神經退化疾病。透過此一課程,期能培養出具備跨學科視野來探究大腦神經科學的學生。
The objective of the course for students is to introduce neuroendocrine–immune (NEI) circuitry from neuron–glial interactions, brain immunoregulation to their pathophysiological functions in central nervous system (CNS). Students will be able to understand that how brain neurons and glia interact with peripheral endocrine and immune system, in order to maintain physiological homeostasis or progress brain diseases such as neurodegenerative disease.

課程學習目標 Course Objectives

  • 探討腦神經內分泌系統與免疫系統之間的交互作用
  • 探究腦內不同細胞之間與大腦外的免疫系統維持正常生理功能和失衡時如何導致疾病發生
  • 培養出具備跨學科視野來探究大腦神經科學的學生
  • 課程進度 Progress Description

    進度說明 Progress Description
    1課程介紹 Introduction
    2腦神經系統:神經元、神經膠質細胞與神經遞質The Nervous System:Neurons , Glia Cells and Neurotransmitter 
    3神經內分泌的免疫調節 Neuro-endocrine Immunoregulation
    4補體系統與神經發炎 Complement System in Neuroinflammation
    5Effects of the Immune System on Brain Neurochemistry免疫系統對腦神經化學的影響
    6腦免疫系統:信號分子的化學與生物學The Brain Immune system: Chemistry and Biology of the Signal Molecular
    7病毒感染相關之神經發炎與疾病(1)Virus Infection Associated Neuronal Inflammation and Diseases (1)
    8病毒感染相關之神經發炎與疾病(2)Virus Infection Associated Neuronal Inflammation and Diseases (2)
    9大腦中的炎症反應調節Regulation of the Inflammatory Response in Brain
    10分子影像應用於大腦疾病診斷與分析Application of Molecular Imaging in Brain Disease and Analysis
    11分子磁振造影於大腦結構與功能影像之應用The Applications of Molecular MRI for Structural, Functional Brain Imaging
    12膠質細胞在中樞神經系統炎症中的角色Role of Glia in CNS inflammation
    13發炎與神經退化疾病The Inflammatory Component of Neurodegenerative Diseases
    14粘多醣與神經退化Glycosaminoglycan in Neurodegeneration
    15Microglia and Neurodegeneration小膠質細胞與神經退化
    16Neuroinflammation and Brain Cancers神經發炎與腦癌
    17學生報告 Student Presentations
    18學生報告 Student Presentations
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    課程是否與永續發展目標相關調查
    Survey of the conntent relevant to SDGs

    本課程與SDGs相關項目如下:
    This course is relevant to these items of SDGs as following:
    • 健康與福祉 (Good health and Well Being)
    • 教育品質 (Quality Education)
    • 永續城市與社區 (sustainable cities and communities)

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No