基本素養 Basic Literacy

Humanistic quality
Civic literacy
Social participation
Global outlook

核心能力 Competence

Basic ability in clinical care
在照顧病人的基本能力下培育基礎與臨床醫學研究的專業素養 轉譯醫學領域專業能力之養成
具有溝通、協調、整合及進行跨領域團隊合作之能力 培養國際觀與外語之能力
Excellent communication skills
Technique for Problem-solving
Habit of lifelong learning

課程概述 Course Description


課程學習目標 Course Objectives

  • 訓練英文科學文章閱讀
  • 學習專題討論報告技巧
  • 提升科學研究之創新思維
  • 課程進度 Progress Description

    進度說明 Progress Description
    19/11 5:00-5:05 主負責老師講解專題討論需注意事項(請參須知)9/11 5:00-6:00 邵愛寧 La ctate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring Journal: Cell Metab. 2019 Dec 3;30(6):1055-1074.e8.
    29/18 5:00-6:00 許修瑞 LINC00265 promotes colorectal tumorigenesis via ZMIZ2 and USP7- mediated stabilization of β-catenin Cell Death & Differentiation (2020) 27:1316–13279/18 6:00-7:00 高明蔚 Regenerative lineages and immune-mediated pruning in lung cancer metastasis Nature Medicine volume 26, pages259–269(2020)
    39/25 5:00-6:00 李純慧 Epigenetic therapy inhibits metastases by disrupting premetastatic niches Nature volume 579, p284–290(2020)9/25 6:00-7:00 張獻元 Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells Science 369, 397–403 (2020)
    410/16 5:00-6:00 李苡潞 In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness. Sci. Transl. Med. 2020 Jun 3;12(546):eaay910110/16 6:00-7:00 許雅婷 Mouse models of neutropenia reveal progenitor-stage-specific defects Nature| Vol 582 | 4 June 2020
    510/23 5:00-6:00 張瑋婷 Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity Ma et al., Sci. Adv. 2020; 6 : eaay2939 29 January 202010/23 6:00-7:00 李柏增 SGLT2 inhibition modulates NLRP3 inammasome activity via ketones and insulin in diabetes with cardiovascular disease NATURE COMMUNICATIONS| (2020) 11:2127 |https://doi.org/10.1038/s41467-020-15983-6|www.nature.com/naturecommunications
    610/30 5:00-6:00 歐穎謙 Non-Crh Glutamatergic Neurons in Barrington's Nucleus Control Micturition via Glutamatergic Afferents from the Midbrain and Hypothalamus Current Biology 29(17) 2775-2789 10/30 6:00-7:00 鄭婉廷 Metabolic regulation of gene expression by histone lactylation Nature. 2019 Oct;574(7779):575-580.
    711/6 5:00-6:00 陳致嘉 A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infectionsNature Immunology 21 , 671–68311/6 6:00-7:00 陳柏偉 Disrupting the platelet internal membrane via PI3KC2 inhibition impairs thrombosis independently of canonical platelet activation Selvadurai et al., Sci. Transl. Med. 12, eaar8430 (2020) 22 July 2020
    811/13 5:00-6:00 翁雅為 Targeting the HIV-infected brain to improve ischemic stroke outcome Nat Commun. 2019 May 1;10(1):200911/13 6:00-7:00 鍾子駿 Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury NATURE NEUROSCIENCE | VOL 23 | MAY 2020 | 676–68
    911/20 5:00-6:00 蔡宗芸 MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo Cell Stem Cell 24, 579–591, April 4, 2019 11/20 6:00-7:00 黃玲育 The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24 Chong et al., 2020, Immunity 53, 1–14
    1011/27 5:00-6:00 呂維勛 GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human beta cell regeneration Science Translational Medicine 12 Feb 2020: Vol. 12, Issue 530, eaaw999611/27 6:00-7:00 余文豪 Distinct immune phenotypes in infants developing asthma during childhood SCIENCE TRANSLATIONAL MEDICINE, 5 February 2020
    1112/4 6:00-7:00 林虞軒
    1212/11 6:00-7:00 黃振 Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD Nature Neuroscience | VOL 23 522 | April 2020 | 520–532
    1312/18 5:00-6:00 汪法悌 IL-18BP is a secreted immune checkpoint andbarrier to IL-18 immunotherapy Nature volume 583, pages609–614(2020).12/18 6:00-7:00 GUPTA TANV
    1412/25 5:00-6:00 Masbuchin Ainun Niza
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No
    3.本課程是否可歸認為學術倫理課程? 否
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics? No
    4.本課程是否屬進入社區實踐課程? 否
    Is this course recognized as a Community engagement and Service learning course? Which community will be engaged? No

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    20200821--Schedule109學年度第1學期臨床醫學研究所博士班專題討論須知 (V3).pdf