基本素養 Basic Literacy

生命科學之專業知識
The professional knowledges of life sciences
科學精神及邏輯辯證
Scientific spirit and logic of dialectical
培養同理心、尊重包容的公民素養
Develop the civic literacy of empathy, respect and inclusive
對生命的社會關懷
The social care of lives
生態保育的哲學觀與正義思維
The philosophy amd justice thinking of ecological conservation
國際宏觀視野與掌握國際科研潮流
Global macro-vision and grasp the trend of international research

核心能力 Competence

充分掌握生命科學專業知識的深度與廣度
Fully grasp the depth of the life sciences expertise
慎密邏輯思考、計量分析與獨立決斷能力
Capable of thinking carefully and logically, measurement analysis and deciding independently
學術交流與溝通能力
Academic communication and interpersonal skills
跨領域知識整合與創新能力
Integration of cross-cutting knowledge and ability to innovate
展現團隊合作及領導統御能力
Capacity to show teamwork amd leadership

課程概述 Course Description

授課內容主要為在分子階層探討真核生物基因的表現與調控、轉錄因子的研究 方法和有關其合成與活性的調控以及開啟有關控制基因表現更高位階的機制新知。

課程學習目標 Course Objectives

  • 對轉錄因子、染色質結構變化、組蛋白密碼有所了解
  • 充實表觀遺傳學與染色質重塑機制之研究領域的理論
  • 探討真核生物基因的表現與調控、轉錄因子的研究方法
  • 課程進度 Course Outline

    週次 Week進度說明 Progress Description
    1Tissue-specific expression of protein and mRNA
    2Transcriptional control-DNA sequence elements and chromatin structure
    3Transcriptional control-transcription factors
    4 Methods for studying transcription facrors
    5 Transcription factors and constitutive transcription
    6Transcription factors and inducible gene expression
    7Transcription factors and cell type- specific transcription
    8Transcription factors and developmentally regulated gene expression
    9Regulation of transcription factor activity
    10Regulation of transcription factor synthesis
    11Transcription factors and human disease
    12DNA binding by transcription factors
    13Activation and repression of gene expression by transcription factors
    14What regulates the regulators?
    15Genomic imprinting and the epigenetic regulation of gene expression
    16Current and future applications of epigenome technology
    17Paper presentation and discussion
    18 Final Exam
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講?
    Is there any industry specialist invited in this course? How many times?
    2.本課程是否規劃含校外實習(並非參訪)?
    Are there any internships involved in the course? How many hours?
    3.本課程是否可歸認為學術倫理課程?
    Is this course recognized as an academic ethics course? In the course how many hours are regarding academic ethics topics?