基本素養 Basic Literacy
Quality of humanism
Logical reasoning and critical thinking ability.
Planning, cooperation, and communication ability.
Creativity and leadership.
Use Multi-cultural point of view to discuss human disposition.
課程概述 Course Description先修科目或先備能力：普通心理學或心理學緒論，修習過認知心理學相關課程尤佳 概述：直至最近，我們對於認知老化的神經基礎建立於兩門很少互相接觸的學科，老化神經科學探討老化對於大腦的效果卻不顧年紀在認知上的改變；而老化認知心理學則是探討老化對於認知的效果而不考量年紀造成的大腦改變。這兩個學科間缺乏溝通的問題正透過聚焦於認知老化以及大腦老化的關聯性的共通研究解決，這些研究正逐漸增加中。這快速增加的研究取向則成為一個新的學門：老化認知神經科學。本課程的目標是要介紹這個新的學門，課程分為四個部份：第一部份介紹大腦老化的非侵入性研究方法，包括結構（例如，容積核磁共振），化學（如多巴胺正子斷層掃描），電生理（如事件關聯電位）和血流動力學（如功能性核磁共振）技術，並討論他們如何能與認知老化行為的連結。第二部分回顧了老化在不同認知功能中的神經活化程度，包括知覺和注意力，意像，工作記憶，長期記憶和前瞻記憶中神經活動的強度。第三部分著重於臨床和應用課題，像是如何區辨正常老化和老年癡呆症的差別，以及如何使用認知訓練對改善因年齡造成的認知能力下降。最後一節介紹了有關認知與大腦老化理論，包括功能性神經影像學證據模式和電腦模擬模型。
Until very recently, our knowledge about the neural basis of cognitive aging was based on two disciplines that had very little contact with each other. Whereas the neuroscience of aging investigated the effects of aging on the brain independently of age-related changes in cognition, the cognitive psychology of aging investigated the effects of aging on cognition independently of age-related changes in the brain. The lack of communication between these two disciplines is currently being addressed by an increasing number of studies that focus on the relationships between cognitive aging and cerebral aging. This rapidly growing body of research has come to constitute a new discipline, which may be called cognitive neuroscience of aging. The goal of this course is to introduce this new discipline. This course is divided into four main sections. The first section describes non-invasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging on neural activity during different cognitive functions, including perception and attention, imagery, working memory, long-term memory, and prospective memory. The third section focuses on clinical and applied topics, such as the distinction between healthy aging and Alzheimer's disease and the use of cognitive training to ameliorate age-related cognitive decline. The last section describes theories that relate cognitive and cerebral aging, including models accounting for functional neuroimaging evidence and models supported by computer simulations.
課程學習目標 Course Objectives
課程進度 Course Outline
|週次 Week||進度說明 Progress Description|
|1||Course orientation Reading preparation|
|2||Chap 1: MRI measures of aging: methodological issues|
|3||Chap 2: Molecular imaging of aging and neurodegenerative disease|
|4||Chap 3: Age differences in structural connectivity: DTI and WMHs|
|5||Chap 4: Age differences in functional connectivity at rest and during cognitive tasks|
|7||Chap 5: Multi-modal imaging of the aging brain Chap 6: Structural and functional imaging of aging: longitudinal studies|
|8||Chap 7: Interpreting age-related differences in memory-related neural activity|
|9||Chap 8: Selective attention and inhibitory control in the aging brain|
|10||Chap 9: Working memory and executive functions in the aging brain|
|11||Chap 10: Neural correlates of age-related slowing|
|12||Chap 11: The aging hippocampus: linking animal and human research|
|13||Chap 12: Episodic memory encoding and retrieval in the aging brain Chap 13: Emotion and emotional memory|
|15||Chap 14: The middle-aged brain: A cognitive neuroscience perspective Chap 15: The modifying role of hypertension in cognitive and brain aging|
|16||Chap 16: Genetics and cognitive neuroscience of aging|
|17||Chap 17: Effects of exercise on cognition, brain structure, and brain function in older adults Chap 18: The link of intellectual engagement to cognitive and brain aging|
|18||Chap 19: Disambiguating preclinical Alzheimer's disease from cognitive aging Chap 20: Late-Life Depression: Translating Neurobiological Hypotheses into novel treatments|
以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.
有關課程其他調查 Other Surveys of Courses1.本課程是否規劃業界教師參與教學或演講? 否
Is there any industry specialist invited in this course? How many times? No
Are there any internships involved in the course? How many hours? No