基本素養 Basic Literacy

核心能力 Competence

具備免疫學、微生物學、寄生蟲學、生物資訊等專業知識,並熟悉相關實驗技術的操作。
Professional knowledge and relevant experimental techniques on Immunology, Microbiology, Parasitology, and Bioinformatics.
能設計實驗並分析和統整實驗數據,以獲得合理結論。
Ability to design and execute experiments, and to analyze the results to obtain logical conclusions.
能以中文和英文進行有效溝通和討論。
Ability to communicate effectively in both Chinese and English.
能活用知識、整合產學及從事轉譯醫學。
Ability to use knowledge creatively in areas such as Industry-University collaborations and translational medicine.

課程概述 Course Description

這是碩士班及博士班兩學分的課程,由數位基礎及臨床老師共同參與教學,此課程主要提供學生整合基礎及臨床基因治療的概念、方法及應用。

課程學習目標 Course Objectives

  • To be familiar with tools and strategies of gene therapy for various diseases
  • To understand the progress and potential for clinical gene and cell therapy
  • To be able to design and conduct gene transfer experiments
  • 課程進度 Progress Description

    進度說明 Progress Description
    1Overview of gene therapy
    2Viral vectors (retrovirus and lentivirus)
    3Viral vectors (adenovirus, adeno-associated virus, and herpesvirus)
    4Viral (poxvirus and alphavirus) and bacterial vectors
    5Non-viral vectors
    6Genome editing technologies for gene therapy
    7DNA vaccine
    8Immunotherapy (preclinical and clinical application)
    9Suicide gene therapy and oncolytic virotherapy
    10Stem cell-based therapy
    11Viral vector-mediated gene transfer in autoimmune arthritis models
    12Gene therapy for genetic diseases
    13Paper discussion (I)
    14Paper discussion (II)
    15Discussion
    16Discussion
    17Discussion
    18Discussion
     以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

    有關課程其他調查 Other Surveys of Courses

    1.本課程是否規劃業界教師參與教學或演講? 否
    Is there any industry specialist invited in this course? How many times? No
    2.本課程是否規劃含校外實習(並非參訪)? 否
    Are there any internships involved in the course? How many hours? No