基本素養 Basic Literacy
無核心能力 Competence
■ 閱讀、理解與運用專業知識
培養學生具備一般及專業領域的研究素養，並富有國際視野之科學涵養
Good reading comprehension on scientific materials and excellent capabilities in applying the learned professional knowledge
To train students to have good backgrounds in general and specialized fields and have global views of science
■ 彙整新知與良好的溝通能力
培養學生具備彙整分子醫學新知與溝通表達研究成果的能力
Abilities of updating and organizing innovative knowledge and demonstrating good communicational skills
To train students to learn efficiently and to apply their knowledge effectively
■ 生物醫學研究技術的應用與能力
培養學生具備生物醫學研究技術的應用與能力
The Abilities and Applications in Biomedical Research and Technology
To nourish students in acquiring both the knowledge and practical applications in biomedical research & technology
■ 解決研究問題的能力
培養學生具備獨立思考與從事分子醫學相關研究領域的能力
Problem-solving skills
To train students to become independent thinkers capable of conducting independent and innovative research in molecular medicine
課程概述 Course Description
人類基因體計畫的執行，疾病與基因的關係因著對基因體功能的瞭解而更加清楚，因此基因體學與功能生物學是應用基因體醫學的基礎，也是現在世界的顯學After the Human Genome Project (HGP), the Functional Genomics attempts to make use of the vast wealth of data produced by genomic and transcriptomic projects (such as genome sequencing projects and RNA-seq) to describe gene (and protein) functions and interactions. The objective of this course is to give students basic knowledge of functional genomic on the dynamic aspects such as gene transcription, translation, regulation of gene expression and protein–protein interactions. By the end of the semester, students will be able to explain and give examples of how functional genomic dissect pathogenesis mechanism of human disease in the level of molecular and gene.
課程學習目標 Course Objectives
課程進度 Progress Description
| 進度說明 Progress Description | |
|---|---|
| 1 | Study the molecular mechanism underlying dissemination of pancreatic ductal adenocarcinoma patients after surgical resection |
| 2 | Question and Discussion |
| 3 | Characterization of role of T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) in Neuronal Function |
| 4 | Question and Discussion |
| 5 | Human DDX3 interacts with the HIV-1 Tat protein to facilitate viral mRNA translation |
| 6 | Question and Discussion |
| 7 | Study on the role of metabolic pathways and their regulation in colorectal cancer |
| 8 | Question and Discussion |
| 9 | Study the regulatory mechanism of SP1 on T-cell lymphoma Invasion And Metastasis 2 (TIAM2) expression in Hepatocellular Carcinoma |
| 10 | Question and Discussion |
| 11 | Study the mechanism of HuR-mediated regulation on FGF9 expression under hypoxia |
| 12 | Question and Discussion |
| 13 | Study the role of FGF9 in male sex determination |
| 14 | Question and Discussion |
| 15 | Study of TIAM2 overexpression induced tumorigenesis |
| 16 | Question and Discussion |
| 17 | Hypoxia induced IRES-mediated RNA witch on FGF9 translation |
| 18 | Question and Discussion |
以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.
有關課程其他調查 Other Surveys of Courses
1.本課程是否規劃業界教師參與教學或演講? 否Is there any industry specialist invited in this course? How many times? No
2.本課程是否規劃含校外實習(並非參訪)? 否
Are there any internships involved in the course? How many hours? No