基本素養 Basic Literacy

核心能力 Competence

具備免疫學、微生物學、寄生蟲學、生物資訊等專業知識,並熟悉相關實驗技術的操作。
Professional knowledge and relevant experimental techniques on Immunology, Microbiology, Parasitology, and Bioinformatics.
能設計實驗並分析和統整實驗數據,以獲得合理結論。
Ability to design and execute experiments, and to analyze the results to obtain logical conclusions.
能以中文和英文進行有效溝通和討論。
Ability to communicate effectively in both Chinese and English.
能活用知識、整合產學及從事轉譯醫學。
Ability to use knowledge creatively in areas such as Industry-University collaborations and translational medicine.

課程概述 Course Description

這是碩士班及博士班兩學分的課程,由數位基礎及臨床老師共同參與教學,此課程主要提供學生整合基礎及臨床基因治療的概念、方法及應用。

課程學習目標 Course Objectives

課程包括基因治療概觀;基因治療之病毒載體;基因治療之非病毒載體;免疫基因治療及DNA疫苗;免疫及細胞基因治療;利用自殺基因、腫瘤裂解性病毒及幹細胞於癌症治療;致癌基因、抑癌基因、細胞週期和基因治療;基因治療於心血管疾病及遺傳性疾病之應用。此外再選用出於英國廣播公司 (BBC) ” Superhuman” 系列的影片來加深學生們的印象,其中“The enemy within”對於腫瘤如何在身體中成長及轉移有深刻的介紹,並敘述數位癌症病人接受基因治療之經過;另外“Killers into cures”則詳細地敘述人類和微生物之間密不可分的關係,甚至可以利用微生物來治療人類的疾病,例如過敏及癌症。

課程進度 Progress Description

進度說明 Progress Description
1Overview
2Viral vectors for gene therapy
3Non-viral vectors for gene therapy
4Immunotherapy and cell therapy
5Immuno-gene therapy and DNA vaccine
6Cancer gene therapy using suicide genes, oncolytic viruses and stem cells
7Oncogenes, tumor suppressor genes, cell cycle & gene therapy
8Films: (I) The Enemy Within (II) Killers into Cures
9Bacterial gene therapy strategies
10Gene therapy for autoimmune diseases
11Gene therapy for genetic diseases
12Film: Gene therapy for cystic fibrosis
13Paper discussion (Gene therapy for cancer or infectious diseases)
14Paper discussion (Gene therapy for neurological disorder)
15Paper discussion (Gene therapy for metabolic or muscle diseases)
16Clinical trial of gene therapy for ischemic cardiovascular disease
17
18
 以上每週進度教師可依上課情況做適度調整。The schedule may be subject to change.

課程學習融入下列議題或具有下列內涵的程度
Immersing the Following Issues or Contents

議題或內容 Issues or Contents關聯性 Correlation
觀光旅遊產業 Tourism 無相關 No correlation
綠色能源產業 Green Energy Industry 間接相關 Indirect correlation
文創產業 Cultural and creative Industry 無相關 No correlation
環境保護 Environmental Protection 間接相關 Indirect correlation
人權教育 Human Rights Education 間接相關 Indirect correlation
服務學習 Service Learning 間接相關 Indirect correlation
性別平等 Gender Equity 間接相關 Indirect correlation
法治教育 Law-Related Education 間接相關 Indirect correlation
工作實務取向 Pragmatic Orientation 直接相關 Direct correlation
生命教育 Life Education 直接相關 Direct correlation
智慧財產權 Intellectual Property 間接相關 Indirect correlation
環境安全 Environmental Safety 間接相關 Indirect correlation
健康醫療照護產業 Health,Medical Treatment, Nursing Industry 間接相關 Indirect correlation
精緻農業產業 Advanced Agriculture 無相關 No correlation
生物科技產業 Biotechnology Industry 直接相關 Direct correlation
學術研究取向 Academic Orientation 直接相關 Direct correlation

有關課程其他調查 Other Surveys of Courses

1.本課程是否規劃業界教師參與教學或演講? 否
Is there any industry specialist invited in this course? How many times? No
2.本課程是否規劃含校外實習(並非參訪)? 否
Are there any internships involved in the course? How many hours? No